NIOSH issues recommended exposure limits for chemicals linked to ‘popcorn lung’

Washington – NIOSH has released recommended limits for controlling occupational exposure to flavoring chemicals diacetyl and 2,3-pentanedione, both of which have been linked to reduced lung function in food flavoring and production industry workers.

Published Oct. 31, Criteria for a Recommended Standard: Occupational Exposure to Diacetyl and 2,3-Pentanedione lists the recommended exposure limits for diacetyl at 5 parts per billion and 9.3 ppb for 2,3-pentanedione as an 8-hour time-weighted average during a 40-hour workweek. NIOSH stated that the limit for 2,3-pentanedione is higher because of “analytical method limitations.” For short-term exposures, the REL is 25 ppb for diacetyl and 31 ppb for 2,3-pentanedione in a 15-minute time span.

The RELs, which align with draft exposure limits NIOSH issued in 2011, are intended to lower the risk of bronchiolitis obliterans – an irreversible lung disease linked to occupational exposure to the chemicals. The disease, also known as “popcorn lung,” was identified among some workers at microwave popcorn packaging plants in the 2000s.

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“We know these flavoring compounds can pose a great risk for workers who may be exposed on the job, causing serious and irreversible damage to their lungs,” NIOSH Director John Howard said in a press release. “This Criteria Document reflects not only our review of the science and understanding of the hazard, but also outlines our recommendations for controlling workplace exposures to these compounds.”

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